Overview Postdoctoral position in HIV 1 RNA structural biology and antiviral drug discovery. The postdoctoral associate will be engaged in a research project funded by the PROMETEO program of Generalitat Valenciana, Spain, and focused on the study of...
Overview
Postdoctoral position in HIV 1 RNA structural biology and antiviral drug discovery.
The postdoctoral associate will be engaged in a research project funded by the PROMETEO program of Generalitat Valenciana, Spain, and focused on the study of the conformational dynamics of the Rev Recognition Element (RRE) in HIV-1 RNA and the discovery of antiviral small molecule agents blocking the complex between this motif and the Rev protein.
A consortium of structural biology, chemistry and virology laboratories at Catholic University of Valencia, University of Barcelona and the IrsiCaixa and ISCIII research institutes in Spain will use state-of-the-art in vitro and in cell techniques to achieve these goals.
HIV/AIDS remains a major global health challenge, especially in low- and middle-income countries.
The successful candidate will work in the laboratory led by José Gallego at Catholic University of Valencia, Spain.
The candidate will apply single-molecule experiments, fluorescence screening, RNA footprinting and computational methods to study the atomic structure and dynamics of the RRE, identify new antiviral candidates and guide the optimization process.
Further information about the laboratory's publication list and research interests can be found in the following sources: the Catholic University of Valencia researcher portal and the lab pages.
Responsibilities
Apply single-molecule experiments, fluorescence screening, RNA footprinting and computational methods to study the RRE structure and dynamics, identify antiviral candidates and guide optimization.
Collaborate with laboratories at Catholic University of Valencia, University of Barcelona, IrsiCaixa and ISCIII in Spain.
Supervise undergraduate students in the laboratory.
Qualifications
Ph.D. required with significant experience in at least two of the following areas:
Structural Biology
Characterization of biomolecule–small molecule interactions using biophysical techniques
Molecular biology and biochemistry methods for RNA and/or protein production and characterization
Good command of English and the ability to work independently and as part of a team; good oral and written communication skills are desirable.
Conditions
Depending on performance, the position will be available for up to 3.5 years, with a gross annual salary of approximately €36,412.
Starting date: November 3, 2025 or earlier.
How to apply
Applications should include a cover letter describing previous research experience and career goals, a CV with publication list, academic records, and at least two reference letters.
In the publication list, mark the two most relevant articles and briefly explain your contribution and why they are important for your application.
Send applications to José Gallego (******) before September 30, 2025.
#J-18808-Ljbffr
Postdoctoral position in HIV 1 RNA structural biology and antiviral drug discovery.
The postdoctoral associate will be engaged in a research project funded by the PROMETEO program of Generalitat Valenciana, Spain, and focused on the study of the conformational dynamics of the Rev Recognition Element (RRE) in HIV-1 RNA and the discovery of antiviral small molecule agents blocking the complex between this motif and the Rev protein.
A consortium of structural biology, chemistry and virology laboratories at Catholic University of Valencia, University of Barcelona and the IrsiCaixa and ISCIII research institutes in Spain will use state-of-the-art in vitro and in cell techniques to achieve these goals.
HIV/AIDS remains a major global health challenge, especially in low- and middle-income countries.
The successful candidate will work in the laboratory led by José Gallego at Catholic University of Valencia, Spain.
The candidate will apply single-molecule experiments, fluorescence screening, RNA footprinting and computational methods to study the atomic structure and dynamics of the RRE, identify new antiviral candidates and guide the optimization process.
Further information about the laboratory's publication list and research interests can be found in the following sources: the Catholic University of Valencia researcher portal and the lab pages.
Responsibilities
Apply single-molecule experiments, fluorescence screening, RNA footprinting and computational methods to study the RRE structure and dynamics, identify antiviral candidates and guide optimization.
Collaborate with laboratories at Catholic University of Valencia, University of Barcelona, IrsiCaixa and ISCIII in Spain.
Supervise undergraduate students in the laboratory.
Qualifications
Ph.D. required with significant experience in at least two of the following areas:
Structural Biology
Characterization of biomolecule–small molecule interactions using biophysical techniques
Molecular biology and biochemistry methods for RNA and/or protein production and characterization
Good command of English and the ability to work independently and as part of a team; good oral and written communication skills are desirable.
Conditions
Depending on performance, the position will be available for up to 3.5 years, with a gross annual salary of approximately €36,412.
Starting date: November 3, 2025 or earlier.
How to apply
Applications should include a cover letter describing previous research experience and career goals, a CV with publication list, academic records, and at least two reference letters.
In the publication list, mark the two most relevant articles and briefly explain your contribution and why they are important for your application.
Send applications to José Gallego (******) before September 30, 2025.
#J-18808-Ljbffr
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