Principal Clinical Scientist (AI Training)

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands and reasons about clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research — ensuring the clinical data powering next-generation AI systems meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role designed for experienced clinical scientists who want to work at the frontier of AI and biomedical research. No AI background required — just deep clinical expertise and a sharp eye for scientific quality.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week
  
  

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and methodology
• Work independently and asynchronously — fully on your own schedule
  
  

Who You Are

• Senior-level experience designing clinical trial protocols for regulatory submission (FDA, EMA, or equivalent)
• Deep expertise interpreting clinical data within regulatory frameworks
• Strong foundation in clinical research methodology, biostatistics, or translational science
• Naturally detail-oriented with high standards for scientific accuracy and consistency
• Clear and effective written communicator able to document feedback in structured formats
  
  

Nice to Have

• Prior experience with data annotation, data quality review, or AI evaluation workflows
• Background in pharmacology, epidemiology, or outcomes research
• Familiarity with AI tools or clinical decision-support systems
• Experience working across multiple therapeutic areas or trial phases
  
  

Why Join Us

• Work directly on frontier AI systems shaping the future of clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with leading AI research labs and teams pushing the boundaries of medical AI
• Potential for ongoing work and contract extension as new projects launch